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Surface Modification Chemistries for Particles and Interfaces

21 August 2015, Friday, 8:30am - 5pm


Boston Park Plaza
50 Park Plaza at Arlington Street
Boston, MA 02116
T. 617.457.2284 | F. 617.457.7456

Registration Form


Surface Modification Chemistries for Particles and Interfaces
Friday, 21 August 2015


The science and technology of nearly all particle-based materials, drug delivery systems, diagnostic methods, controlled release systems, composites, etc., involve on every length scale, from the molecular to the macro, surface and interfacial phenomena that can be tuned by varying the surface and interfacial energy and by varying the specific chemical interactions and chemical groups populating such surfaces and interfaces. This is particularly true in formulating multiphase fluids for coatings, and in making pigments and other particulate additives stable in coating fluids, prepolymers and resins of a particular coated layer or composite film. Being able to take a particle and make it “happy” in a dispersion environment that otherwise would be unstable and lead to coating defects and untoward dispersion destabilization is a skill that will make the student more competitive in the broad advanced materials and pharmaceutical industries. This course augments introductory organic, inorganic, and colloid chemistry courses by providing a broad range of practical applications of physical and synthetic chemistries that enable the student to achieve many different kinds of surface and interfacial modifications.

Basic physical-chemical methods, basic organic and inorganic coupling chemistries, and living polymerization methods are reviewed and applied to achieving diverse forms of surface and interfacial modification suitable for nanoparticles through high volume and high surface area planar substrates. The emphasis is on the application of various chemistries to enable highly value-added materials to be made in a chemically stable and robust manner.

The course is targeted at the advanced undergraduate and beginning graduate student level and will be useful to R&D chemists, materials scientists and engineers, and innovators in developing a toolbox of methods to use in optimizing formulations for advanced materials and applications.

This course reviews and illustrates the practical applications of physical, organic, and inorganic chemistry, as learned in undergraduate courses, and presents methods, for the constructive chemical surface modification of particulate and planar substrates used in diverse applications in the coatings, materials, and pharmaceutical industries. The course focuses on physical methods such as layer-by-layer assembly, physical adsorption, and upon diverse chemistries including thiol-driven self-assembly on particular substrates, diverse coupling chemistries, sol-gel silane-based chemistries, living polymerization methods, grafting chemistries including click chemistry, surface-initiated polymerization, encapsulation chemistries, and applications in controlled release, formulating composites, and advanced applications in diagnostics and array technologies.

A comprehensive reading list and extensive references are provided to facilitate the practical review of the topics covered as the need for detail arises in the workplace and development laboratory.

Registration Form

Topics Covered:

Course Overview
  Why modify surfaces? What is surface modification? How can we modify surfaces? Surface Energetics, Physical Methods, Chemical Methods, Surface Reconstruction, Coupling Chemistries, HighEnergy Treatments, Wet Chemical Treatments, Grafting, Targeting, Diagnostics

High Energy Treatment
  Plasma, UV, Sputtering, CVD, Fluidized Bed Coating, Surface Functionalization, Wet Chemical Treatment, Biomaterials, Composites, Aerosol Assisted Particle Coating

Layer-by-Layer Assembly
  LbL Methods, Suitable Polymers, Synthetic Nacre, Covalent LbL, LbL with Diverse NanoObjects

Coupling Chemistries
  Arene Radical Cations, Hydroxyl Functions, Amine FUnctions, Thiol Reactive Groups, Carboxyl Functions, Coupling Agents, Click Chemistries, PEG Surfaces

Silane Coupling
  Sol-Gel Chemistry, Silane Coupling Agents, Hydrosilation, UV Curable Nanocomposites, Supramolecular Ionic Liquids

ATRP and Related Living Polymer Polymerization
  ATRP, Reverse ATRP, Applications, Surface Initiated Polymerization, Nitroxyl-Mediated LFRP, RAFT Polymerization, ATRP in Air

Anionic and Cationic Living Polymer Polymerization
  LASIP on Silica, Brushes by LASIP, Anionic Polymerization in Clays

Physical Adsorption
  Effects on Dispersion Stability, Adsorption Analyses, Specific Surface Area Effects, Experimental Methods, Ion Adsorption, Polymer Adsorption

Grafting Chemistries
  Surface Initiated Polymerization, Brush Packing, Graft Radical Polymerization, Photografting, Grafting Free Chains within Preexisting Brushes

Encapsulation and Controlled Release
  Motivation, Phase Change Encapsulation, Encapsulation by Polymer Adsorption, Encapsulation by Polymerization, Encapsulation by Solvent Extraction, Emulsification Methods, Encapsulation by LbL

Advanced Printing and Diagnostics
  A Burgeoning New Industry, Gene Analysis by Arrays, Microcontact Printing, Hyperbranched Polymers, Patterned Adsorption, Affinity Contact Printing, Microcontact Printing, Functional Antibody Arrays, Protein Immobilization



The basic course fee of $1095 (or discounted amount; see Registration Form) includes a book of slides in electronic form on a USB stick, luncheon, and coffee breaks mid-morning and mid-afternoon. Discounts for full-time students are available (see Registration Form).

Registration Form


The course venue is the Boston Park Plaza [50 Park Plaza at Arlington Street, Boston, MA 02116, USA; Tel: 617.457.2284].

Directions & Map

© 2015 Particles Conference
tel 1-585-413-8264; fax 1-585-482-7795